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Following proper titration schedules can shorten this adjustment period

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Danuglipron lost out on both efficacy and safety, so its discontinuation was not unexpected

Persistent vomiting or diarrhoea can lead to dehydration, which in turn may increase the risk of acute kidney injury a class-relevant concern also noted in the Summary of Product Characteristics (SmPC) for approved GLP-1 receptor agonists such as semaglutide

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Use body composition tests, anthropometric measures, and patient-reported outcomes to evaluate treatment effect and inform individualized clinical decision making