Annu Rev Biochem 52:711760 Njalsson R, Norgren S, Larsson A, Huang CS, Anderson ME, Luo JL (2001) Cooperative binding of gamma-glutamyl substrate to human glutathione synthetase
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By now, there are a few studies on the pharmacokinetics and bioavailability of intranasal lamotrigine in rats and mice, showing promising results with high brain-targeting efficacy [247, 248], but further research has to be done especially regarding efficacy
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