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Spontaneous reports through systems like the MHRA Yellow Card scheme cannot establish frequency or definitively confirm causality
The most practical concern for any breastfeeding mother considering GLP-1 therapy is whether she can maintain adequate nutrition while experiencing appetite suppression
The discontinued NCT02472717 trial investigating liraglutide in PsA further illustrates both the pioneering nature and the challenges inherent in this research field (82)
unexposed pregnancies
Abbreviations IBD: Inflammatory bowel disease UC: Ulcerative colitis GLP-1: Glucagon-like peptide-1 GIP: Glucose-dependent insulinotropic polypeptide anti-TNF: Anti-tumor necrosis factor JAK: Janus Kinase JAKi: Janus Kinase Inhibitor FCP: Fecal calprotectin CRP: C-reactive protein IQR: Interquartile range LDL: Low-density lipoprotein HDL: High-density lipoprotein MASLD: Metabolic dysfunction-associated steatotic liver disease References Kaplan GG, Windsor JW
Diabetologia (2016) 59(2):26674.10.1007/s00125-015-3795-1 8 OdawaraMMiyagawaJIwamotoNTakitaYImaokaTTakamuraT
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