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S.JemalA
J Pediatr 2014;165(1):59-64
Think Tylenol with an instant pain reduction instead of a delayed response, paired with the bypass of the liver, which gives you a much safer way to take the drug
These effects were blocked by sulfasalazine, an inhibitor of the xCT transporter, which incorporates cystine (precursor of GSH) and extrudes extracellular glutamate, an agonist of the inhibitory mGlu2/3 receptor, which lowers the synaptic glutamatergic tone
None of this is surprising, since oxidative stress is closely linked with other forms of aging as well
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