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Accordingly, whereas PPAR agonists (fibrates) are classically assumed to improve lipid and cholesterol metabolism via their action on the liver, agonists at PPAR (thiazolidinediones) are assumed to improve insulin sensitivity by enhancing adipose tissue differentiation and fatty acid uptake 10,11,23
They report how the math is described, not a recommended dosing schedule
[13] [11] Other GLP-1 receptor agonists have demonstrated renoprotective effects in dedicated outcome trials, though these findings cannot be automatically extrapolated to tirzepatide