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For instance: people with obesity are more likely to develop type 2 diabetes people with obesity are at an increased riskof developing Alzheimers later in life people with type 2 diabetes are also more likely to develop Alzheimers disease Alzheimers disease is associated with insulin resistance in the brain, with some scientists referring to Alzheimers as type 3 diabetes obesity, type 2 diabetes, and Alzheimers all involve inflammation, and GLP-1 agonists have an anti-inflammatory effect studies in animal models of dementiahave shown that GLP-1 agonists can protect rats brains from damage

This hypothesis, while speculative, could explain the peptides ability to normalize both deficiency and excess states across diverse neurotransmitter disturbances

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This reduction is induced by a decline in the secretion of IL-33 in murine models [135]

The starting dose is usually low to allow for a smooth transition, and over the course of several weeks, the dosage is increased to reach the maintenance dose that provides the most benefit for weight loss and blood sugar control

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