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High-dose Vitamin C IV therapy may be appropriate for individuals seeking additional immune support, particularly those experiencing frequent illness, prolonged fatigue, or increased inflammatory burden

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Why slow titration reduces side effects The standard four-week intervals between dose increases exist because research shows that slow titration reduces nausea by approximately 30% compared to faster escalation

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this list is not exhaustive Antacids Colchicine (treatment of gout) H2 Blockers (Zantac, Tagamet, Pepcid) Metformin Diabetes drug (Glucophage) PPIs Proton pump inhibitors (Omeprazole, Nexium, Prevacid, Protonix) Nitrous oxide anaesthesia Nitrous oxide recreational abuse (Laughing gas / Whippets / Hippy crack) Mycifradin sulphate (Neomycin) antibiotic Para aminosalicylates antibiotic Phenytoin (Dilantin) anti-epileptic Potassium chloride (K-Dur) Cholestyramine (Questran) Chemotherapy and radiation treatment Increased demands Chronic Hemoltic anaemia Hyperthroidism Multiple myeloma Myelopproliferative disorders Neoplasms Pregnancy Some patients may never find out the cause of their condition, this does not mean that they should be denied B12 injections which are, safe, inexpensive and the most efficient treatment for their deficiency