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Tuy nhin liu dng c bn l 1 ngy ung 2 vin, mi ln ung trc ba n 30 pht hoc sau ba n 1 gi

NHK is encoded by a nonsense mutation of 1-antitrpysin that results in a truncated product which is retained in the ER and undergoes ER-associated degradation, resulting in ER stress in diverse cell types (Nagasawa, Higashi, Hosokawa, Kaufman, & Nagata, 2007