10.1152/ajpregu.00128.2019 79 PriyadarshiniM.LaydenB
Glucagon-like peptide-1 (GLP-1) receptor agonists such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound)a dual GIP/GLP-1 receptor agonisthave transformed the management of type 2 diabetes and obesity
In the Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results study, a numerically higher incidence of complications associated with DR, such as panretinal photocoagulation, anti-VEGF injection, vitreous hemorrhage, and blindness, was observed, although results did not reach clinical significance
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Oral GLP-1s are probably the most anticipated innovation within this category, given their convenient, non-invasive nature relative to current injectable formulations