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"A Study of Retatrutide (LY3437943) Once Weekly in Participants Who Have Obesity or Overweight (TRIUMPH-4)." NCT05931367
In terms of weight loss, if you have a vitamin B12 deficiency, which is likely, you will lose some of the vitamin B12 shot in the first 48 hours, but at least 50% of it will be stored in your liver
Your healthcare provider will monitor you, especially with the first dose
Some contraindications (reasons not to take B12 shots) include: Allergies to cyanocobalamin or methylcobalamin Kidney or liver disease Eye issues, especially if you have Lebers disease A current infection If youre taking medication related to bone marrow You should talk to your doctor about the above conditions before getting B12 injections
They contain essential amino acids and nutrients that contribute to overall health
To put it in context, nicotinamide has shown signs of liver toxicity only at doses around 3,000 mg per day or higher
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