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doi: 10.1210/jc.2003-030049 142 StonehouseAHHolcombeJHKendallDM

Payers want to see that the prescriber is following the FDA-approved escalation protocol: starting at 2.5mg weekly for 4 weeks, then increasing to 5mg weekly, with subsequent increases as clinically indicated

Clinical studies support its use for attention, mental energy, and working memory

As a result, serious illness can occur, including frequent infections such as pneumonia

Determining the number of patients from those infected who later experience persistent symptoms is extremely difficult although it is estimated that between 10% and 45% experience long COVID (205)

Additionally, increased ChaC2 expression targets the Cadherin 1 gene (encoding E-cadherin) mutation, resulting in E-cadherin loss, increased epithelial-mesenchymal transformation and lymph node metastasis, ultimately contributing to the low differentiation of breast cancer (50)