Notably, differences in the timing of disease onset have been observed even among monozygotic twins, and in a case report, one sibling remained symptom-free for up to 13 years after the other had already developed the disease [20]
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It should be used with caution in neonates, premature infants, children, and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged 70 years and above) after consulting the doctor
Long-term outcome of mesna, ifosfamide, mitoxantrone, etoposide (MINE) regimen as a consolidation in patients with aggressive non-Hodgkin lymphoma responding to CHOP
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