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We also see these obesity-related diseases now starting in our adolescents, so there certainly is harm to ignoring it and not offering them treatment, Ashley Shoemaker, MD, MSCI, associate professor of pediatrics and pediatric endocrinology at Monroe Carell Jr
If persistent, dose reduction may be necessary
Any changes in libido are likely indirect, resulting from weight loss, hormonal shifts, metabolic improvements, or psychological factors rather than direct drug effects on sexual physiology
10.1111/acer.12854 13 KanoskiS
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Retatrutide, because it adds glucagon receptor activation, may cause additional metabolic effects that neither semaglutide nor tirzepatide produce, including greater fat oxidation and potentially different hunger pattern changes
