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Landmark mechanistic work showed that SCFAs trigger GLP-1 secretion through FFAR2, and that mice lacking this receptor have blunted SCFA-driven GLP-1 release and impaired glucose tolerance
Schmitt, A
Over-Stimulation of NO (Nitric Oxide): We mentioned BPC-157 can boost nitric oxide for healing, but too much NO isnt a good thing
At 1.7 mg, the metabolic effects are substantial
Pharmacologic treatment of overweight and obesity in adults
2022;14:mfab072
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