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Nat Rev Methods Primer
L., Neuschwander-Tetri, B
For example, in the case of HIV, IgG3 has been shown to be generally more effective at neutralization than IgG1 of the same specificity, possibly related to the greater flexibility of IgG3 associated with a longer hinge region, which allows for more restricted epitopes to be accessed, although there are some exceptions 97,98,99,100
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