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It is dominated by whole-animal and electrophysiological observation rather than molecular pharmacology, because the molecular pharmacology was never possible
A pilot study investigating gut microbiomes of 52 patients receiving either Dulaglutide or Liraglutide determined a microbial signature of GLP-1RA responders ( n = 34) and non-responders ( n = 18) (Tsai et al., 2022)
Dont run one-size-fits-all GLP-1 programs
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Weston uses this information to curate customized lifestyle plans that treat symptoms related to chronic disease, elevate daily energy levels and improve long-term health
The most clinically useful research will come from prospective studies that specifically enroll autoimmune patients starting tirzepatide for metabolic indications and track autoimmune disease activity alongside metabolic outcomes
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