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Furthermore, impaired cerebral metabolism appears to be an early-stage biomarker for ADRD, as several studies have shown reduced glucose metabolism in the hippocampus and posterior cingulate prior to observation of overt clinical symptoms (i.e., cognitive impairment) (Kumar et al., 2022
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The gut releases it in response to food intake
(1) Ng, A., Griffith, J
Out of those participants, 85% lost at least 5% of their weight (versus 26% with placebo), 69% lost at least 10% (vs 12%), 54% lost at least 15% (vs 6%), and 34% lost at least 20% (vs 3%)
PMID: 40134805
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