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Oestrogen dependence may be due to the upregulation of the 17-hydroxysteroid dehydrogenase-1 and aromatase genes, whereas progesterone resistance may result from the failure of progesterone receptor activation and transcription of progesterone target genes [99]

Clinicians should exercise heightened caution when considering these compounds in patients receiving anticoagulant or antiplatelet therapy, given their possible influence on hemostasis and wound-healing dynamics

1992 Dec 26;673:53-7

A breast lift can reshape and recontour the breasts, but does not noticeably reduce size