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For a research tool that is a serious limitation, and it is the single most important thing to understand before designing an experiment with it

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Medvidovic-Grubisic et al

BPC-157's angiogenic effects via VEGF upregulation directly address this limitation by improving the vascular environment at the injury site

After an initial loading phase of frequent injections (often daily or weekly), many patients can transition to monthly or less frequent maintenance doses, depending on how well their levels stabilize

And some of these studies in rats involved a complete transection, not just a partial tear, but a complete cut of a given ligament or tendon or nerve pathway