Article updated 12/17/2025 to reflect recent FDA communications, regulatory clarifications and clinical context related to GLP-1 medications
All types of research reports, including case reports and case series, were included
Product Specifications Research Overview PT-141, also indexed as bremelanotide, is a cyclic lactam heptapeptide analogue of alpha-melanocyte-stimulating hormone with the sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH (CHNO, 1025.2 g/mol, CAS 189691-06-3)
Statements Data availability statement The datasets presented in this article are not readily available because the datasets analyzed in this study are subject to restrictions due to the use of the TriNetX Research Network platform and institutional data-use agreements
So being aware of regularity in your bowel movements is essential
All authors critically revised the paper for intellectual content and approved the submitted versions and the final version of the manuscript