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10.1016/j.tibs.2021.07.003 85 RhrigF.SchulzeA
And then the second generation ones like Semaglutide and now Tirzepatide, and there are many related compounds coming on the market, showed up towards of ten, 15, even 20 plus percent body weight loss, which was really unseen before with any other anti-obesity medications
doi: 10.1016/S2213-8587(23)00356-X 13 JastreboffAMKaplanLMFrasJPWuQDuYGurbuzSet al
They often go hand in hand
Eli Lilly re-entered the spotlight in 2014 with Trulicity (dulaglutide) and again in 2022 with Mounjaro (tirzepatide)a dual agonist that activates both GLP-1 and GIP receptors, showing even greater weight loss results in trials
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