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Daily subcutaneous or intramuscular injection, ~300-500 mcg/day in standard use

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In rats, gavage of trimetazidine (10 mg/kg/day) for 7 days prior to induction of acute myocardial ischemia preserved the mitochondrial structure, improved respiratory control ratio and mitochondrial complex I activity, as well as mitochondrial biosynthesis and fusion [137]

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