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Oxcarbazine: Oxcarbazine appears to function as a prodrug
importantly, these agents do not cause immunosuppression and carry no increased infectious risk relevant to biologic-combination scenarios
No significant associations were found between any individual GLP-1 receptor agonist and risk of sepsis, abscess, gangrene, or other serious infections
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Postmarketing reports also include ileus, intestinal obstruction and severe constipation with fecal impaction
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