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Alterations in GSSG generation, recycling, and/or efflux have all been reported to be associated with correspondingly altered cell vulnerability to cell death in response to various cellular stresses

Chronic dietary l-carnitine supplementation in mice altered cecal microbial composition, markedly enhanced synthesis of TMA and TMAO, and increased atherosclerosis, but this did not occur if intestinal microbiota was concurrently suppressed

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These experiments suggest a half-life longer than two days