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Patients with pre-existing conditions such as chronic kidney disease, heart failure, or those taking diuretics, ACE inhibitors, or other medications affecting electrolyte balance require particularly careful monitoring

This alcohol-free formula ensures gentle care, making it ideal for all skin types, from sensitive to normal

However, it is generally used in cycled protocols (e.g., 8-16 weeks) rather than continuous long-term therapy

Close collaboration with gastroenterologists and adherence to current guidelines are also important

Their independent effects on the gastrointestinal system warrant consideration when used concurrently