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Prolonged periods of sitting or lying down increase the risk of blood clots
The alternative is a single-stage approach, where an intraoperative cholangiogram (IOC) is performed during gallbladder surgery to identify bile duct stones , which are then removed during the same operation using laparoscopic bile duct exploration
Measured outcomes are the post-treatment changes in plasma amino acid concentrations and metabolic measurements
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Importantly, there were no cardiovascular adverse events, no clinically significant changes in blood pressure or heart rate, no alterations in thyroid function, no immunogenicity with no anti-AOD-9604 antibodies detected, and no signs of tolerance or receptor desensitization