Until recently, therapeutic strategies remained limited to lifestyle interventions, with few pharmacological options demonstrating meaningful clinical benefit
Research11 min read Semaglutide and Depression: What Clinical Data Shows What does clinical trial data actually show about semaglutide and depression risk
*Correspondence: Binghong He, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
The SELECT trial, published in 2023, enrolled 17,604 adults with overweight or obesity and established cardiovascular disease but without diabetes
Advise people that ongoing pharmacotherapy, in conjunction with behaviour modifications, is likely to be needed to maintain a healthy weight and effectively manage CVD risk in the long term
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