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If the genetic testing doesnt confirm PCD, another test, known as a cultured skin fibroblast carnitine assay, could be performed

L-Carnitine and intestinal inflammation [PMID: 21419279] Laboratory literature summary: L-Carnitine and intestinal inflammation

The liver is the principal site for the hydroxylation of cholecalciferol at carbon 25 by 25-hydroxylase enzymes (CYP2R1 and CYP27A1) to form 25(OH)VD 3

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As the toxicity through poor health rises, leading to an increase in free radicals, the use of methionine will increase (see above)