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high pharmacologic doses (1-3 g/day) can cause hypotension, insulin resistance, and hepatotoxicity
This is an advanced protocol requiring more monitoring
[1] The authors reported that methylquinolinium analogs with primary-amine substitutions displayed high permeability from passive and active transport across membranes, measured using two standard in-vitro models: the parallel artificial membrane permeability assay (PAMPA) and Caco-2 human intestinal cell monolayers
So, 1000 mcg is the same as 1 mL
A key study showed that this intervention improved insulin sensitivity in mice, suggesting it helps restore metabolic flexibility