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GLP-1RAs can suppress local inflammation caused by agonistic anti-CD3 antibody through intraepithelial lymphocytes (IELs) (Wong et al., 2022)
FEBS J 273:55895597
GLP-1s are a critical area of concern for employers and other plan sponsors as a cost driver in the pharmacy benefit
The most common side effects are gastrointestinal: nausea (affecting roughly 20-30% of users at higher doses), diarrhea, vomiting, constipation, and decreased appetite
Diener, C
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