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Since clinical trials consistently show tirzepatide producing greater average weight loss than semaglutide, it might seem counterintuitive to switch in this direction
The primary difference is manufacturing oversight rather than drug efficacy or safety
Its mechanism of action is not fully clarified, but it seems to be fundamentally mediated by the inhibition of cyclooxygenase at the central level, especially COX-2, decreasing the synthesis of prostaglandins
Many users prefer weekend mornings so any initial side effects occur during days off work
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