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[1] Primary mechanisms: modulation of the nitric oxide (NO) system via upregulation of eNOS, activation of VEGFR2-Akt-eNOS signaling for angiogenesis, and enhancement of antioxidant defenses (HO-1 upregulation)

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These techniques are widely used in metabolite analysis of plasma, urine, and tissue samples, and also play an important role in biomarker discovery

This has generated strong research interest in epithalon as a potential treatment for a variety of inflammatory ailments including arthritis and ulcerative colitis