Diabetes 68(6):11211129 Grespan E, Giorgino T, Natali A, Ferrannini E, Mari A (2021) Different mechanisms of GIP and GLP-1 action explain their different therapeutic efficacy in type 2 diabetes
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GLP-1 therapy is generally recommended for individuals diagnosed with type 2 diabetes who require additional glycemic control, patients with a body mass index (BMI) greater than 27, especially those with weight-related comorbidities, and those not achieving target blood glucose levels with metformin or other oral hypoglycemic agents
It can be produced by the body itself, but is also influenced by nutrition, stress levels, sleep quality and exposure to environmental stressors
Various products are in different stages of research and development (2, 68)