In the last few years, various GSH modulation-enhanced combinational therapy strategies have been extensively exploited, accompanied by the development of versatile metal-based nanosystems with different structures, functionalities, and treatment performances ( In view of the rapid development of GSH-responsive and -exhausting metal nanomedicines in potentiating cancer therapy, we summarize and outline the recent advancements, mechanisms, prospects, and challenges in this field from different strategies (Scheme 1)
C.KwongH.LeungY
Glutathione biosynthesis: -glutamylcysteine synthetase from rat kidney
Zhao X, Wang M, Wen Z, Lu Z, Cui L, Fu C, Xue H, Liu Y, Zhang Y
Andreassen, et al (2001) The growth hormone secretagogue ipamorelin counteracts glucocorticoid-induced decrease in bone formation of adult rats Growth Hormone & IGF Research, Volume 11, Issue 5, October 2001, Pages 266-272
17 DPSC implantation has been shown to promote pulp regeneration and root development, proving effective in the treatment of tooth injuries caused by trauma and demonstrating the clinical safety and efficacy of this approach