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In the SUSTAIN clinical trial program evaluating Ozempic for type 2 diabetes, injection site reactions were reported in 1.2-1.4% of patients receiving semaglutide compared to 0.7% receiving placebo

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It also serves as a substrate for various antioxidant enzymes, including glutathione peroxidase and glutathione reductase, which further amplify its protective effects

They eventually began applying the same strategy to knee pain and arthritic finger symptoms