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The potential risks to the developing fetus, coupled with the evolving hormonal landscape of pregnancy, underscore the importance of individualized decision-making guided by healthcare professionals
The FDA has approved a handful of GLP-1 and dual GIP/GLP-1 medications for chronic weight management
Cancer Risk A review and discussion stated: ROS production is significantly increased in cancer cells because of mitochondrial dysfunction, altered metabolism, and frequent genetic mutations, resulting in an accumulation of large amounts of oxidized protein, DNA, and lipids as an adaptive response, cancer cells harbor elevated levels of ROS-scavenging molecules
Still, GLP-1s are contraindicated in people with a personal or family history of MTC or multiple endocrine neoplasia syndrome type 2 (MEN2)
However, they need further evidence-based studies
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