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During inflammatory processes, triglycerides undergo hydrolysis, forming free fatty acids (FFA) (Zhu et al., 2022), which are toxic to hepatocytes and induce apoptosis through both extrinsic and intrinsic pathways (LeFort et al., 2024)
The normalization of intestinal permeability, while not formally included among STRIDE-II targets, represents a desirable future endpoint that may further refine the assessment of barrier restoration
Skipping it isn't just a missed nutritional opportunity it may actually reduce the hormonal response your medication is trying to support
Most people see lab changes within 412 weeks
But that framing is built on DXA data and the assumption that DXA-detected lean mass loss is, in fact, muscle
Research and clinical usage have demonstrated its well-tolerated
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