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Since mitochondrial ROS contribute to cardiolipin oxidation and are controlled by antioxidants (Mari et al., 2008, 2009), mGSH arises as an important modulator of apoptotic cell death by indirectly controlling the redox state of cardiolipin (Mari et al., 2008
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Data suggest that semaglutide may lower the 10-year risk of developing type 2 diabetes by as much as 60% in people with overweight and weight-related complications or with obesity while on treatment
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Earlier framings of "0.34 partial agonist at GCGR" or "0.4 softened agonist at GLP-1R" mistook potency ratios (EC50_LY EC50_native) for efficacy multipliers (E_max_LY E_max_native) and are retracted
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