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In a small RCT of Alzheimers disease, liraglutide improved cognitive function and brain volume over one year (Edison P et al, Alzheimers & Dementia 2021;17(Suppl 9):e057848)

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In cohort studies, combination therapy was associated with a lower risk of MACE (RR 0.56 [95% CI 0.43, 0.71] and the kidney composite endpoint (RR 0.48 [95% CI 0.32, 0.73] relative to SGLT2 inhibitor or GLP-1 RA monotherapy

This infographic provides a breakdown of considerations that apply to each investigation approach.

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A recovery peptide conversation may be appropriate only after urgent or serious causes have been ruled out