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Whether the insulinotropic action of GLP-1RAs, overcoming the reduced incretin effect, might ameliorate NAFLD is however still uncertain
Thus, GIP is a likely candidate for mediating some of the therapeutic actions of DPP-4 inhibition, and the recent development of a GIP receptor antagonist suitable for use in clinical studies (50) should allow this hypothesis to be tested
An essential role for ectodomain shedding in mammalian development
10.1179/1743132812Y.0000000156 42 KaliaL
For example, high alcohol consumption can contribute to liver and heart problems
These are all FDA-approved medications that have been extensively studied
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