Patients with active inflammation, recent flares, severe malnutrition, strictures, or unstable medication regimens should generally avoid GLP-1 initiation until disease control improves
The apparent lack of a direct effect was noted due to the in vitro environment not mimicking the inherent environment of a tendon in vivo
Keep in mind that the weekly administration day can be changed as long as the time between doses is a least 2 days (48 hours)
Back DJ, Breckenridge AM, MacIver M, et al
Recovery support (training soreness, performance consistency) Sleep quality support Body composition goals (paired with nutrition + resistance training) Healthy aging / vitality goals Who Is a Good Candidate
This is the patient group in which the STEP-HFpEF, STEP-HFpEF DM and SUMMIT trials demonstrated robust benefits