No trial has formally measured this
India had the third largest number of people with obesity as of 2022, behind China and the US, according to a study in The Lancet, with numbers surging as junk food consumption becomes more commonplace
For example, a randomized trial in overweight and obese women found that those taking bupropion had different average weight changes than those on placebo
This shift promotes hunger, stimulates GH secretion, and supports adaptive responses to energy deficit, including increased food-seeking behaviour and energy conservation
Similarly to TB-500, it has recently gained a lot of attention on social media
doi: 10.1016/j.bioactmat.2026.03.032 22 DutourAPaselloMFarrowLAmerMEntz-WerlNNathrathM