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in part, it may be seen that it is desirable to concomitantly inhibit PDE-5 and increase production of cGMP by means of different pathways, thereby resulting in optimal therapeutic benefit with minimal adverse effects

Our findings also show that while the benefits of GLP-1 drugs are significant, their use does come with some added risk of diabetic retinopathy, suggesting that physicians need to carefully monitor the eye health of kidney transplant recipients with diabetes who are started on these drugs, senior investigator Mara McAdams-DeMarco said in a news release

Halloum W, Dughem YA, Beier D, Pellesi L