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Its therapeutic activity may not involve an AT mechanism
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Yang J, Phi JH
Peptide / Compound Information Source: PubChem for research reference only
By examining a variety of Bcr-Abl downstream signals including pAkt-S473, pS6K-T389 in the PI3K/Akt/mTOR pathway, and pStat5-Y694, we confirmed these signals similarly elevated in these two different transformed cells
500 Additionally, PepGens PGN-EDO51, designed to skip exon 51 in the DMD gene, has shown promising results in Phase I clinical trials and is now in Phase II (NCT06079736)
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