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The challenge, of course, is that discontinuing semaglutide often leads to weight regain, which brings its own set of sexual function implications
The tradeoff is that evening injection sometimes causes sleep disruption
Tirzepatide further slows gastric emptying, which can exacerbate existing gastroparesis and make blood sugar control more erratic
As an initial trial examining switching to oral therapy for maintenance of weight reduction, and in the absence of a widely agreed upon definition or calculation to assess maintenance of weight reduction, several endpoints, including additional sensitivity analyses, were evaluated in this trial regarding maintenance and overall change
2022 Mar 30;11(7)
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