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These medications cross the blood-brain barrier and directly influence neural activity
Diabetologia 59, 426435
The most common side effects of metformin include: Stomach pain or upset Diarrhea Nausea Bloating and gas Heartburn and indigestion Headache Metallic taste What are the side effects of Ozempic
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Subsequently, these two groups independently reported that the synthetic GLP-1 peptide acted as a potent stimulator of insulin secretion in isolated perfused rat pancreas (24) and isolated perfused pig pancreas (23), respectively, thus implicating GLP-1 as the second incretin
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