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An altered pH in the solvent can cause them to denature, aggregate, or simply fail to dissolve properly

In summary, imbalances in the composition of bacterial community in the intestine can lead to transient intestinal dysfunctions, barrier modulation, and chronic disease states such as IBD

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Animal studies have indicated benefit in the GI tract, liver, pancreas, ligaments, muscles, tendons, cornea, heart, brain, and nerves