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The 2023 Endocrine Society Clinical Practice Guideline on Obesity in Adults recommends that clinicians counsel all patients of reproductive age about the need for effective contraception during GLP-1 therapy and a minimum 2-month pre-conception washout period [8]
As more people initiate GLP-1 RAs for diverse indications, understanding these nuanced experiences will be key to improving adherence, minimizing harm, and optimizing outcomes
Heart rate changes are one of the most misunderstood effects of GLP-1 receptor agonists
The pharmacy visit becomes an incidental part of the trip rather than the sole purpose, which makes the economics work regardless of distance
Additionally, ROS activate the hypoxia-inducible factor-1 alpha (HIF-1) pathway, leading to increased expression of vascular endothelial growth factor (VEGF) and the formation of retinal neovascularization [186]