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Materials and methods: Data from 5,242 participants of The Maastricht Study were used (mean age: 59.78.8 yrs, 50.5% women)
Stress signals the hypothalamus (the part of the brain that regulates body functions) to release cortisol
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Furthermore, several transcription factors, such as Neurod1, Rfx6, Arx, Foxa1, Foxa2, Pax4, and Pax6 regulate the differentiation of EEC subpopulations [24] (Fig
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