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Significant changes in the gut microbiota composition, particularly an increase in Bacteroides barnesiae , as well as increases in serum sphingolipid metabolites (Sphinganine 1-phosphate, Sphingosine, and Sphingosine-1-phosphate) and hippocampal proteins (Sptlc1, Enpp5, Enpp2), were strongly correlated
the HOMA insulin resistance index was calculated 48
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It comprises bacteria, fungi, viruses, and archaea, with bacteria accounting for the majority
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